| Current Issue Volume 2 (8) August 2009 |
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Authors:Elizabeth Asch, AB, Deborah Levine, MD, Ivan Pedrosa, MD, Jonathan L. Hecht, MD, PhD, Jonathan Kruskal, MD, PhD
Harvard Medical School, Boston, MA; and the Departments of Radiology (D.L., I.P., J.K.) and Pathology (J.L.H.), Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215 |
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Rationale and Objectives
The aim of this study was to assess potential quality assurance (QA) issues in the diagnosis and characterization of adnexal masses on pelvic computed tomographic (CT) and magnetic resonance (MR) imaging studies.
Materials and Methods
Images from 128 women who had oophorectomies during a 16-month period with CT and/or MR studies within 5 years of surgery (145 CT scans from 103 women and 49 MR studies from 42 women, with 17 having both MR and CT studies) were reviewed by three radiologists who assigned QA scores of 0 (no QA issue), 1 (minor issue with minimal impact on clinical care), or 2 (major issue with potential impact on clinical care). The difficulty of diagnosis was assigned a score of 0 (very difficult diagnosis to make), 1 (difficult but possible to make the diagnosis), or 2 (diagnosis should be made). The incidence of adnexal QA issues was calculated using total CT and MR pelvic examinations performed on women during the interval.
Results
Twenty-nine QA issues were identified in 28 women in 17 of 145 CT studies (11.7%) and 12 of 49 MR examinations (24.5%) in women having adnexal surgery (17 of 11,194 [0.15%] of female pelvic CT studies and 12 of 603 [2.0%] of female pelvic MR studies performed in the time interval). Issues included missed lesions, lesions misidentified as leiomyomas, fat described in the lesion but not seen histologically, postmenopausal status of patient not considered, ultrasound correlation not recommended, and confusion of right and left sides.
Conclusion
Errors in CT and MR studies regarding the diagnosis and characterization of adnexal masses in a highly enriched population of women undergoing adnexal surgery are common. Knowledge of the types of QA issues found in CT and MR studies of adnexal masses should aid in decreasing future errors.
Key Words: CT, MR, adnexal mass, ovarian malignancy, quality assurance |
| Date: August 2009 |
DOI: 10.1016/j.acra.2009.02.016 | Acad Radiol 2009; 16:969–980 |
| © 2009 AUR |
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Authors: T.C. Lee, R.I. Aviv, J.M. Chen, J.M. Nedzelski, A.J. Fox and S.P. Symons
From the Division of Neuroradiology (T.C.L., R.I.A., A.J.F., S.P.S.), Department of Medical Imaging, and Department of Otolaryngology-Head and Neck Surgery (J.M.C., J.M.N.), Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.
Please address correspondence to Sean Symons, BASc, MPH, MD, FRCPC, DABR, Sunnybrook Research Institute, 2075 Bayview Ave, AG31, Toronto, Ontario, Canada M4N 3M5; e-mail: sean.symons@sunnybrook.ca |
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BACKGROUND AND PURPOSE: The CT grading system for otosclerosis was proposed by Symons and Fanning in 2005. The purpose of this study was to determine if this CT grading system has high interobserver and intraobserver agreement.
MATERIALS AND METHODS: All 997 petrous bone CTs performed between December 2000 and September 2007 were reviewed. A total of 81 subjects had CT evidence of otosclerosis on at least 1 side; 68 (84%) had bilateral disease. Because otosclerosis was clinically suspected in both ears of all 81 subjects even if CT evidence was only unilateral, both petrous bones (162 in total) were included. Two blinded neuroradiologists independently graded disease severity using the Symons/Fanning grading system: grade 1, solely fenestral; grade 2, patchy localized cochlear disease (with or without fenestral involvement) to either the basal cochlear turn (grade 2A), or the middle/apical turns (grade 2B), or both the basal turn and the middle/apical turns (grade 2C); and grade 3, diffuse confluent cochlear involvement (with or without fenestral involvement). One reviewer repeat-graded the petrous bone CTs to determine intraobserver agreement with a 7-month intervening delay to mitigate recall bias.
RESULTS: There were 154 agreements (95%) comparing the first grading of reviewer 1 with that of reviewer 2 ({kappa} = 0.93). When the repeat 7-month delayed grading of reviewer 1 was compared with that of reviewer 2, there were 151 (93%) agreements ({kappa} = 0.90). Therefore, mean interobserver agreement was excellent (mean {kappa} = 0.92). There were 155 agreements (96%) comparing the original grading of reviewer 1 with the delayed grading ({kappa} = 0.94), demonstrating excellent intraobserver agreement.
CONCLUSIONS: A recently published CT grading for otosclerosis on the basis of location of involvement yielded excellent interobserver and intraobserver agreement. |
| Date: August 2009 |
DOI: 10.3174/ajnr.A1558 | American Journal of Neuroradiology 30:1435-1439 |
| © 2009 American Society of Neuroradiology |
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Authors: Gorka Bastarrika1, Christian Thilo1,2, Gary F. Headden3, Peter L. Zwerner2, Philip Costello1 and U. Joseph Schoepf1,2
1 Department of Radiology and Radiological Science, Medical University of South Carolina, Ashley River Tower, MSC 226, 25 Courtenay Dr., Charleston, SC 29425.
2 Division of Cardiology, Department of Medicine, Medical University of South Carolina, Charleston, SC.
3 Division of Emergency Medicine, Department of Medicine, Medical University of South Carolina, Charleston, SC. |
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OBJECTIVE. The purpose of this article is to describe the current role of ECG-synchronized CT in the evaluation of patients with acute chest pain (triple rule-out) in the emergency department. We discuss clinical contexts of the chest pain algorithm, technical improvements that have enabled CT to attain its current role for this application, scan protocols and radiation considerations, the evidence base regarding diagnostic and prognostic performance, and initial data on the cost-effectiveness of this promising emerging test.
CONCLUSION. Currently available evidence suggests that CT-based approaches with modern scan technology are safe, accurate, and potentially cost-saving, although large-scale clinical trials are needed to ascertain the precise role of CT in the evaluation of acute chest pain.
Keywords: acute chest pain - acute coronary syndrome - coronary artery disease - CT - triple rule-out |
| Date: August 2009 |
DOI:10.2214/AJR.08.2265 | AJR 2009; 193:397-409 |
| © American Roentgen Ray Society |
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Authors:Boaz K. Karmazyn, MDa, Richard B. Gunderman, MD, PhDa, Brian D. Coley, MDb, Ellen R. Blatt, MDc, Dorothy Bulas, MDd, Lynn Fordham, MDe, Daniel J. Podberesky, MDf, Jeffrey Scott Prince, MDg, Charles Paidas, MDhi, William Rodriguez, MDjk
a Riley Hospital for Children, Indiana University, Indianapolis, Indiana
b Columbus Children's Hospital, Columbus, Ohio
c The Children's Hospital, Denver, Colorado
d Children's National Medical Center, Washington, DC
e University of North Carolina, Chapel Hill, North Carolina
f Wilford Hall Medical Center, Lackland Air Force Base, Texas
g Primary Children's Medical Center, Salt Lake City, Utah
h Tampa General Hospital, Tampa, Florida
i American Pediatric Surgical Association, Deerfield, Illinois
j The Office of Pediatric Therapeutics in the Office of the Commissioner, US Food and Drug Administration, Rockville, Maryland
k American Academy of Pediatrics, Elk Grove Village, Illinois |
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Developmental dysplasia of the hip (DDH) affects 1.5 of every 1,000 caucasian Americans and less frequently affects African Americans. Developmental dysplasia of the hip comprises a spectrum of abnormalities, ranging from laxity of the joint and mild subluxation to fixed dislocation. Early diagnosis of DDH usually leads to low-risk treatment with a harness. Late diagnosis of DDH in children may lead to increased surgical intervention and complications. Late diagnosis of DDH in adults can result in debilitating end-stage degenerative hip joint disease. Screening decreases the incidence of late diagnosis of DDH. Clinical evaluation for DDH should be performed periodically at each well-baby visit until the age of 12 months. There is no consensus on imaging screening for DDH. Consideration for screening with ultrasound is balanced between the benefits of early detection of DDH and the increased treatment and cost factors. In addition, randomized trials evaluating primary ultrasound screening did not find significant decrease in late diagnosis of DDH. In the United States, hip ultrasound is selectively performed in infants with risk factors, such as family history of DDH, breech presentation, and inconclusive findings on physical examination. Ultrasound for DDH should be performed after 2 weeks of age because laxity is common after birth and often resolves itself. A pelvic radiograph can optimally be performed after the age of 4 months, when most infants will have ossification centers of the femoral heads.
Key Words: ACR Appropriateness Criteria, pediatric, ultrasound, development dysplasia of the hip, screening, subluxation, dislocation |
| Date: August 2009 |
DOI: 10.1016/j.jacr.2009.04.008 | J Am Coll Radiol 2009;6:551-557 |
| © 2009 American College of Radiology |
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Authors:Azusa Kitao, MD; Yoh Zen, MD; Osamu Matsui, MD; Toshifumi Gabata, MD and Yasuni Nakanuma, MD.
From the Departments of Radiology (A.K., O.M., T.G.) and Human Pathology (A.K., Y.Z., Y.N.), Kanazawa University Graduate School of Medical Science, 13-1 Takaramachi, Kanazawa 920-8640, Japan.
Address correspondence to A.K. (e-mail: kitao@rad.m.kanazawa-u.ac.jp).
Author contributions: Guarantors of integrity of entire study, all authors; study concepts/study design or data acquisition or data analysis/interpretation, all authors; manuscript drafting or manuscript revision for important intellectual content, all authors; approval of final version of submitted manuscript, all authors; literature research, A.K., O.M.; clinical studies, A.K., Y.Z., O.M., T.G., Y.N.; statistical analysis, A.K.; and manuscript editing, A.K., Y.Z., O.M., Y.N. |
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Purpose: To clarify the changes that occur in drainage vessels of dysplastic nodules and hepatocellular carcinoma (HCC) during hepatocarcinogenesis by using computed tomography (CT) during arterial portography (CTAP) and CT during hepatic arteriography (CTHA), with histologic findings as the reference standard.
Materials and Methods: Institutional ethics committee approval and informed consent were obtained. According to the findings at CTAP and CTHA, 46 surgically resected hepatocellular nodules were classified into three types: type A (n = 18) (equivalent or decreased portal perfusion compared with background liver at CTAP, decreased arterial perfusion, and no corona enhancement [perinodular contrast material drainage] at CTHA), type B (n = 13) (no portal perfusion, increased arterial perfusion, and thin (=2-mm) corona enhancement), or type C (n = 15) (no portal perfusion, increased arterial perfusion, and thick (>2-mm) corona enhancement). We compared the histopathologic features and microangioarchitecture between the types.
Results: Type A nodules histologically consisted of dysplastic nodules and well-differentiated HCC; type B and C nodules were moderately differentiated HCC. Replacing growth was commonly observed in type A nodules, whereas compressing growth was more frequently seen in types B and C. Sixty percent of type C nodules had a fibrous capsule. There were significantly fewer intranodular hepatic veins in types B and C. Serial pathologic slices demonstrated continuity from intranodular capillarized sinusoids to hepatic veins in type A nodules and to surrounding hepatic sinusoids in type B nodules. In type C nodules, intranodular capillarized sinusoids were connected to extranodular portal veins either directly or through portal venules within the fibrous capsule.
Conclusion: Drainage vessels of HCC change from hepatic veins to hepatic sinusoids and then to portal veins during multistep hepatocarcinogenesis. |
| Date: August 2009 |
DOI: 10.1148/radiol.2522081414 | Radiology, 252, 605-614. |
| © RSNA, 2009 |
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